Gene interactions and pathways from curated databases and text-mining

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DDIT4 — PRKAB2

Text-mined interactions from Literome

Schneider et al., Neoplasia (New York, N.Y.) 2008 (Carcinoma, Squamous Cell...) : Interestingly, AMPK inhibition before prolonged hypoxia prevented REDD1 expression, thereby sustaining mTOR activity
Zannella et al., Radiother Oncol 2011 (Colorectal Neoplasms) : AMPK was required for IR induced expression of the mTOR inhibitor REDD1 , indicating that AMPK restrains mTOR activity through multiple mechanisms