Zhang et al., Oncogene 2013
(Cell Transformation, Neoplastic...) :
We show that p130 Crk associated substrate (p130Cas) is a direct substrate of PTPN14 and that PTPN14 specifically regulates p130Cas phosphorylation at tyrosine residue 128 ( Y128 ) in colorectal cancer ( CRC ) cells
Schlaepfer et al., Mol Cell Biol 1997
:
FAK induced phosphorylation of p130cas in the Src 1-298 cells promoted the SH2 domain dependent binding of the Nck adaptor protein to p130cas , which may facilitate signaling to ERK2
Tamura et al., Cancer Res 1999
(Neoplasm Invasiveness) :
Overexpression of p130Cas increased total tyrosine phosphorylation levels of p130Cas without affecting those of FAK ; however, although p130Cas could reverse PTEN inhibition of cell invasion and migration, it did not rescue cell growth in U87MG cells