Gene interactions and pathways from curated databases and text-mining

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COL4A4 — CTGF

Text-mined interactions from Literome

Qi et al., American journal of physiology. Renal physiology 2005 (Fibrosis...) : CTGF ( 20 ng/ml ) induced fibronectin and collagen IV secretion in primary cultures of human proximal tubule cells (PTC) and cortical fibroblasts ( CF ) compared with control values ( P < 0.005 in all cases ) ... TGF-beta(1) induced a greater increase in fibronectin and collagen IV secretion in both PTC ( P < 0.01 ) and CF ( P < 0.01 ) compared with that observed with CTGF alone
Qi et al., American journal of physiology. Renal physiology 2006 : Our studies further demonstrate that in the CTGF gene silenced cells, CTGF partially mediates TGF-beta(1) induced fibronectin and collagen IV secretion