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CRK — NOX1

Text-mined interactions from Literome

Pomerance et al., J Biol Chem 2000 : Diphenylene iodonium, a potent inhibitor of NADPH oxidase ( s ), and ascorbic acid, an effective free radical scavenger, suppressed TSH- or forskolin stimulated p38-MAPK phosphorylation, indicating that the generation of reactive oxygen species plays a key role in signaling from cAMP to p38-MAPKs
Puntambekar et al., J Neurochem 2005 : Inhibition of NADPH oxidase activity also attenuated NGF dependent p38 MAPK activation
Qin et al., Free Radic Biol Med 2006 : These results suggest that angiotensin II-induced apoptosis is mediated via NADPH oxidase activation probably through p38 MAPK activation, a decrease in Bcl-2 protein, and caspase activation
Wu et al., Free Radic Biol Med 2009 (Inflammation...) : Collectively, the results of this study and those of previous reports indicate that the conversion of cardiomyocytes to a proinflammatory phenotype in sepsis involves two distinct pathways : NADPH oxidase mediated phosphorylation of IKK and p38 MAP kinase mediated phosphorylation of p65
Zhao et al., Am J Physiol Heart Circ Physiol 2012 (Disease Models, Animal...) : Anisomycin treatment resulted in an increase in Nox2 protein and the phosphorylation of Nox2, which was blocked by inhibition of p38