Gene interactions and pathways from curated databases and text-mining

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CHI3L1 — STAT3

Text-mined interactions from Literome

Singh et al., J Biol Chem 2011 (Glioma) : Furthermore, YKL-40 is a migration factor for primary astrocytes, and its expression is controlled by both NFI-X3 and STAT3 , which are known regulators of gliogenesis ... Activation of STAT3 by oncostatin M induced YKL-40 expression in astrocytes, whereas expression of a dominant negative STAT3 had a suppressive effect
Hughes et al., J Pathol 2012 (Acute-Phase Reaction) : During second phase involution, chitinase 3-like 1 , which has been associated with wound healing and chronic inflammatory conditions, is dramatically up-regulated by Stat3