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CHI3L1 — STAT3
Text-mined interactions from Literome
Singh et al., J Biol Chem 2011
(Glioma) :
Furthermore,
YKL-40 is a migration factor for primary astrocytes, and its expression is
controlled by both NFI-X3 and
STAT3 , which are known regulators of gliogenesis ... Activation of
STAT3 by oncostatin M
induced YKL-40 expression in astrocytes, whereas expression of a dominant negative STAT3 had a suppressive effect
Hughes et al., J Pathol 2012
(Acute-Phase Reaction) :
During second phase involution,
chitinase 3-like 1 , which has been associated with wound healing and chronic inflammatory conditions, is dramatically
up-regulated by
Stat3