◀ Back to CDKN1A
CDKN1A — CENPK
Text-mined interactions from Literome
Oki et al., Cancer Lett 1999
(Adenocarcinoma...) :
p33 ( ING1 ) cooperates with p53 and negatively
regulates cell growth by activating transcription from the
p21/WAF1 promoter even though it has no significant sequence similarity to p53
Zhu et al., Chin J Cancer 2004
(Bone Neoplasms...) :
Ectopic overexpression of
p33 ( ING1b ) increased the protein expression of p53 and strongly
enhanced the expression of endogenous
p21 ( WAF1 ) and Bax
Gong et al., Mol Cell Biol 2006
:
As shown previously, ectopic expression of
p33 ( ING1b )
increased levels of the
p21 ( Waf1 ) cyclin dependent kinase inhibitor upon UV-induced DNA damage ... Overexpression of 14-3-3 inhibited the
up-regulation of
p21 ( Waf1 ) by
p33 ( ING1b ), consistent with the idea that mislocalization blocks at least one of ING1 's biological activities