Gene interactions and pathways from curated databases and text-mining

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CDKN1A — CENPK

Text-mined interactions from Literome

Oki et al., Cancer Lett 1999 (Adenocarcinoma...) : p33 ( ING1 ) cooperates with p53 and negatively regulates cell growth by activating transcription from the p21/WAF1 promoter even though it has no significant sequence similarity to p53
Zhu et al., Chin J Cancer 2004 (Bone Neoplasms...) : Ectopic overexpression of p33 ( ING1b ) increased the protein expression of p53 and strongly enhanced the expression of endogenous p21 ( WAF1 ) and Bax
Gong et al., Mol Cell Biol 2006 : As shown previously, ectopic expression of p33 ( ING1b ) increased levels of the p21 ( Waf1 ) cyclin dependent kinase inhibitor upon UV-induced DNA damage ... Overexpression of 14-3-3 inhibited the up-regulation of p21 ( Waf1 ) by p33 ( ING1b ), consistent with the idea that mislocalization blocks at least one of ING1 's biological activities