Gene interactions and pathways from curated databases and text-mining

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CDK2 — IL1A

Text-mined interactions from Literome

Murai et al., J Biol Chem 2001 (Melanoma) : IL-1 quickly enhances the protein expression of the CDK inhibitor p21(cip1)
Lok et al., J Lab Clin Med 2006 (Pre-Eclampsia) : IL-1alpha enhanced the expression of IL-1alpha, IL-2, IL-6, and IL-8 ; nuclear factor of kappa light chain enhancer in B-cells ( NFkappaB ) -1, NFkappaB-2, and NFkappaB-inhibitor ; cyclin dependent kinase inhibitor and monocyte chemotactic protein-1 ; and transiently increased tissue factor expression
Hwang et al., IUBMB Life 2007 : In contrast to cyclin D1, IL-1beta triggered down-regulation of the CDK inhibitor, p21