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CD40LG — PRL
Text-mined interactions from Literome
Chavez-Rueda et al., Clin Exp Rheumatol 2005
(Lupus Erythematosus, Systemic) :
Prolactin effect on CD69 and
CD154 expression by CD4+ cells from systemic lupus erythematosus patients
Peeva et al., J Immunol 2006
(Genetic Predisposition to Disease...) :
The increase in costimulation due to
prolactin mediated up-regulation of both CD40 on B cells and
CD40L on T cells would appear to play a central role in lupus induction in this model
Wang et al., Nan Fang Yi Ke Da Xue Xue Bao 2007
(Lupus Erythematosus, Systemic) :
[
Effect of
prolactin on
CD40/CD154 expression on peripheral blood mononuclear cells in patients with systemic lupus erythematosus ] ...
CD154 significantly increased on the PBMCs in SLE patients with high serum prolectin level in comparison with that in patients with normal prolactin level or the normal controls ( P < 0.05 ). When the PBMCs were incubated with recombinant human prolactin, CD154 expression was significantly
increased in SLE patients with normal serum
prolactin level ( P < 0.05 ), but not in the normal control group ( P > 0.05 )