◀ Back to CD28
CD28 — CDC42
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Salazar-Fontana et al., J Immunol 2003
:
The signaling pathway coupling
CD28 to cytoskeletal rearrangements required Src related kinase activity and
promoted Vav phosphorylation and
Cdc42 activation independently of the zeta-chain associated kinase ( ZAP-70 )
Müller et al., Traffic 2006
:
Consistent with their inability to activate
Cdc42 and Rac1 in
response to the ligation of
CD3/CD28 , T cells exposed to MV fail to acquire a morphology consistent with spreading and lamellopodia formation