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CAV2 — PRKCA
Text-mined interactions from Literome
Sukumaran et al., J Biol Chem 2002
(Escherichia coli Infections) :
Overexpression of a dominant negative form of
caveolin-1 containing mutations in the scaffolding domain
blocked the interaction of
phospho-PKCalpha with caveolin-1 and the E. coli invasion of HBMEC, but not actin cytoskeleton rearrangement or the phosphorylation of PKCalpha
Tourkina et al., J Biol Chem 2005
(Fibrosis...) :
In another, increased
PKCalpha induces
caveolin-1 expression, which in turn inhibits MEK/ERK activation and collagen expression
Wang et al., Cancer Res 2007
(Carcinoma, Squamous Cell) :
Within this ordered complex of signaling molecules, the ability of CD82 to associate with
PKC-alpha requires the presence of
caveolin-1 , whereas the interaction of caveolin-1 or PKC-alpha with EGFR requires the presence of CD82 and ganglioside GM3