Cho et al., J Biol Chem 2003
:
Therefore, in the present experiment, we investigated the modulation of caveolin status in senescent cells to determine the effect of caveolin on mitogenic signaling efficiency and cell cycling Linge et al., Int J Biochem Cell Biol 2007
(Adenocarcinoma...) :
As predicted, we find that caveolin-1 amount increases in response to bleomycin-treatment and that modulation of caveolin-1 affects p21 and p53 levels, cell cycling , and senescence ( SA-beta-galactosidase activity )