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CA2 — SMC5
Text-mined interactions from Literome
Wang et al., Biophys J 2008
:
A comparative fit of the model simulations to experimental data predicts 1 ), that airway and arteriole SMC contraction is initiated by fast activation by Ca2+ of MLCK ; 2 ), that airway
SMC , but not arteriole SMC, is
inhibited by a slower activation by
Ca2+ of MLCP ; and 3 ), that the presence of a contractile agonist inhibits MLCP to enhance the Ca2+ sensitivity of airway and arteriole SMCs
Strøbaek et al., Br J Pharmacol 1996
:
2. Stimulation of the human coronary artery
SMC ( HCASMC ) with extracellular ATP at concentrations of 0.1-100 microM induced a transient
increase in
[Ca2+ ] i from a resting level of 49 +/- 21 nM to a maximum of 436 +/- 19 nM