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CA2 — PTX3

Text-mined interactions from Literome

Troncone et al., J Neurophysiol 2003 : Ca2+ imaging in normal-Ca2+ saline showed that omega-Ptx-IIA partially blocked stimulus dependent presynaptic Ca2+ signals, and the blockade was almost completely reversible
Satoh et al., J Neurochem 1991 : The PTX induced increase both in [ 3H ] ACh release and in [ Ca2+ ] i was almost completely abolished by the combination of Ca2+ deprivation and Na+ concentration reduction
Sontag et al., Biochem J 1991 (Second Messenger Systems) : PTX also potentiated Ca2 ( + ) -evoked catecholamine release from permeabilized chromaffin cells, suggesting that PTX substrate ( s ) regulate the exocytotic machinery at a step distal to the rise in intracellular Ca2+
Ozaki et al., Comp Biochem Physiol C 1987 : PTX increased uptake of 45Ca2+ in normal as well as low-Na+ solutions with similar time course as the increase in muscle tension
Monroe et al., Am J Physiol 1995 : PTx also caused a concentration dependent biphasic rise in the cytosolic free Ca2+ concentration ([Ca2+]i) by enhancing entry of extracellular Ca2+ ( Ca ( e ) 2+ )
Poggi et al., Eur J Immunol 1996 (Mast-Cell Sarcoma) : Unlike the differential effect on cell adhesion, both the intracellular calcium [Ca2+ ] i increase and phosphoinositide breakdown mediated via LFA-1 were consistently inhibited in a dose dependent manner by both Ctx and Ptx
Ishii et al., Naunyn Schmiedebergs Arch Pharmacol 1997 : PTX ( 10 nM ) induced a sustained rise in cytosolic Ca2+ ( [ Ca2+ ] i ), which was resistant to verapamil but suppressed by omission of extracellular Ca2+
Amano et al., Naunyn Schmiedebergs Arch Pharmacol 1997 : In this study, we examined the effect of PTX on the cytosolic Ca2+ concentration ([Ca2+]i) in the endothelium of rabbit aortic valves loaded with fluorescent Ca2+ indicators, fura-PE3 or fluo-3 ... ATP and thapsigargin also increased [ Ca2+ ] i. Imaging of [ Ca2+ ] i with a confocal microscope revealed that PTX increased [ Ca2+ ] i in all endothelial cells studied ( n = 13 ) ... The PTX induced increase in [ Ca2+ ] i was partially inhibited by ouabain and was abolished by removal of external Ca2+ although decrease of Na+ concentration in the incubation medium was ineffective
Nishizaki et al., J Neurophysiol 1998 : All three agonists evoked potassium currents and increased the intracellular free Ca2+ concentration ([Ca2+]i) , and these effects were inhibited by the broad G-protein inhibitor guanosine-5'-O- ( 2-thiodiphosphate ) ( GDPbetaS ) but not by the Gi/o-protein inhibitor pertussis toxin ( PTX )