Gene interactions and pathways from curated databases and text-mining

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CA2 — PC

Text-mined interactions from Literome

Levin et al., J Toxicol Environ Health 2007 : Exposure to the three non-coplanar PCBs significantly increased cytosolic Ca2+ in dolphin neutrophils, while PCB 180 significantly increased cytosolic Ca2+ in beluga neutrophils ... In experiments with Ca2+-free medium, only PCB 153 increased cytosolic Ca2+ in dolphin neutrophils, though the increase was less than that observed with Ca2+ supplemented medium, suggesting that extracellular Ca2+ was the predominant source for the rise in cytosolic Ca2+
Levitsky et al., Membr Biochem 1986 : Activation of isolated Ca2+-ATPase in the presence of 0.1 mM EGTA results in PCB- release into the medium and additional TPP+ binding to the enzyme
Wong et al., Mol Pharmacol 1996 : Neither 2,2',3,5',6- nor 3,3',4,4',5-pentachlorobiphenyl ( < / = 10 microM ) alters the activity of the skeletal isoform of sarcoplasmic/endoplasmic reticulum Ca2+ -ATPase or the cardiac isoform of sarcoplasmic/endoplasmic reticulum Ca2+ -ATPase, and PCB induced Ca2+ release can be fully blocked by either microM ryanodine or ruthenium red
Hazen et al., Dev Neurosci 1997 : Effect of carbonic anhydrase inhibition and acetoacetate on anaplerotic pyruvate carboxylase activity in cultured rat astrocytes
Wong et al., Mol Pharmacol 1997 : PCB 95 alone enhances thapsigargin evoked Ca2+ release and therefore diminishes the loading capacity of SR vesicles