Gene interactions and pathways from curated databases and text-mining

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CA2 — ESR1

Text-mined interactions from Literome

Bulayeva et al., Am J Physiol Endocrinol Metab 2005 (Calcium Signaling...) : Mechanisms of membrane estrogen receptor-alpha mediated rapid stimulation of Ca2+ levels and prolactin release in a pituitary cell line
Li et al., J Biol Chem 2005 : The transcriptional activity of estrogen receptor-alpha is dependent on Ca2+/calmodulin ... Work from several laboratories has documented a Ca2+ dependent interaction between ERalpha and calmodulin
Muchekehu et al., Cell Calcium 2008 : The estrogen receptor antagonist ICI 182,780 ( 1 microM ) prevented the E2-induced effects suggesting a role for the estrogen receptor in the release of [Ca2+ ] i from ryanodine-receptor gated stores
Roan et al., J Recept Signal Transduct Res 2008 (Calcium Signaling) : Diethylstilbestrol induced estrogen receptor dependent [Ca2+ ] i rises and apoptosis in Chinese hamster ovary ( CHO ) cells
Castoria et al., Int J Cancer 1996 (Breast Neoplasms...) : It is a 67 kDa protein under denaturating conditions, binds calmodulin-Sepharose in a Ca2+ dependent manner, is stimulated by Ca2+ and calmodulin, phosphorylates exogenous actin, is activated by the estradiol-receptor complex
Minshall et al., J Clin Endocrinol Metab 1998 (Coronary Disease...) : Steroid concentrations in venous blood, coronary artery estrogen receptor ( ER ) and progesterone receptor (PR) localization, and isolated vascular muscle cell ( VMC ) Ca2+ and protein kinase C responses to serotonin and U46619 ( a thromboxane A2 mimetic ) were measured