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BCL2 — BRCA1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: BCL2 — BRCA1 (physical association, affinity chromatography technology) Laulier et al., Cancer Res 2011*
• IRef Biogrid Interaction: BCL2 — BRCA1 (direct interaction, fluorescent resonance energy transfer) Laulier et al., Cancer Res 2011*
• IRef Intact Interaction: BRCA1 — BCL2 (physical association, proximity ligation assay) Laulier et al., Cancer Res 2011*
• IRef Intact Interaction: BRCA1 — BCL2 (colocalization, confocal microscopy) Laulier et al., Cancer Res 2011*

Text-mined interactions from Literome

McEachern et al., J Cell Biochem 2003 : Full length BRCA1 transactivated the estrogen receptor-alpha (ERalpha) and BCL2 promoters as well as AP-1, SRE, and CRE containing promoters
Laulier et al., Cancer Res 2011 : In this study, we identified the breast cancer tumor suppressor BRCA1 , which plays an essential role in homologous recombination ( HR ), as a target for Bcl-2 in the repression of HR