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APOE — MTTP

Text-mined interactions from Literome

Engle et al., Biochim Biophys Acta 2001 : Both Pluronic L-81, an inhibitor of chylomicron secretion, and BMS-197636-02, a microsomal triglyceride transfer protein inhibitor , blocked the secretion of both TG and PC
Ueshima et al., Life Sci 2004 (Arteriosclerosis) : Microsomal TG transfer protein (MTP) is essential for the synthesis of both chylomicron in the intestine and very low density lipoprotein in the liver
Jiang et al., J Virol 2009 : At higher concentrations, however, MTP inhibitors blocked apoE expression and secretion and consequently suppressed the formation of HCV particles
Ables et al., J Lipid Res 2012 : In contrast, inhibition of microsomal triglyceride transfer protein ( MTP ) reduced chylomicron secretion after oral fat/retinol loads, but with accumulation of dietary TG and retinoids in the small intestine