◀ Back to APOB
APOB — CRP
Text-mined interactions from Literome
van Tits et al., Arterioscler Thromb Vasc Biol 2005
:
These findings suggest that : ( 1 ) CRP and annexin A5 at physiological concentrations bind to distinct sites of negatively charged phospholipids present in oxidized LDL ; ( 2 )
CRP enhances binding of oxidized
LDL to monocytic/macrophage-like cells via Fcgamma receptors ; and ( 3 ) annexin A5 does not antagonize the CRP induced enhanced binding of oxidized LDL to U937 cells
Ji et al., Int J Biochem Cell Biol 2006
(Atherosclerosis) :
Interaction of modified
C-reactive protein and low-density lipoprotein was
mediated synergistically by both electrostatic association with
ApoB and hydrophobic insertion into lipid layer
Pontet et al., Biochimie 1979
:
Moreover,
CRP in the serum is shown to be in the bound form only, and the binding
involves Low Density Lipoproteins (LDL) exclusively
Mookerjea et al., Arterioscler Thromb 1994
:
Rat
C-reactive protein causes a charge modification of
LDL and stimulates its degradation by macrophages ... The degradation of the modified
125I-LDL by rat peritoneal macrophages was increased more than twofold in the
presence of rat
CRP ... In contrast, the degradation of
125I-acetyl-LDL by macrophages was not
affected by rat
CRP , although acetylated LDL inhibited the rat CRP stimulated degradation of 125I-LDL