Gene interactions and pathways from curated databases and text-mining

◀ Back to APOB

APOB — CD36

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Yamaguchi et al., Thromb Res 2000 (Thrombasthenia) : Oxidized-LDL dose-dependently inhibited bindings of both GS95 and OKM5 antibodies to platelet CD36 , while PS-liposome inhibited the binding of GS95 but not OKM5 or FA6-152
Feng et al., J Lipid Res 2000 : Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-gamma
Wintergerst et al., Eur J Biochem 2000 : Here we present evidence that CD36 is involved in oxidized LDL ( OxLDL ) -induced apoptosis in human monocyte derived macrophages
Ishii et al., Circ Res 2004 (Arteriosclerosis) : Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages : activation by oxidatively modified LDL and 4-hydroxynonenal
Jostarndt et al., Biochem Pharmacol 2004 : Since free oxidized polyunsaturated fatty acids are PPARgamma ligands, we studied the effects of LDL modified by the simultaneous action of sPLA2 and 15-lipoxygenase ( 15LO ) on CD36 expression and PPARgamma activation in monocytic cells ... Importantly, LDL modified by sPLA2 and 15LO did not efficiently induce upregulation CD36 in PPARgamma-deficient macrophage differentiated embryonic stem cells confirming a role of PPARgamma in CD36 expression in cells stimulated with enzLDL ... Our data show that LDL modified with physiologically relevant enzymes stimulates CD36 expression in non differentiated monocytes and that this process involves PPARgamma activation
Koller et al., Pathophysiol Haemost Thromb 2006 : The role of CD36 in platelet binding by oxidised LDL is well established, although additional receptors may exist
Graessler et al., Diabetologia 2007 (Glucose Intolerance) : Glycoxidised LDL isolated from subjects with impaired glucose tolerance increases CD36 and peroxisome proliferator-activator receptor gamma gene expression in macrophages
Luangrath et al., Arterioscler Thromb Vasc Biol 2008 : Our objective was to define the physiological role of CD36 in both native LDL and oxLDL metabolism in mice
Maruyama et al., Arch Biochem Biophys 2008 : We previously demonstrated that Nrf2 regulates oxidized LDL mediated CD36 expression in macrophages
Pedrosa et al., Biochim Biophys Acta 2010 : These results provide evidence that CD36 expression induced by LDL ( - ) is Nrf2 dependent
Granados-Principal et al., Mol Nutr Food Res 2012 (Atherosclerosis) : SQ caused a dose dependent reduction of CD36 in the presence of native and moderate LDL in monocytes and macrophages
Babaahmadi Rezaei et al., Iran Biomed J 2013 : Compare the Effect of Eicosapentaenoic Acid and Oxidized Low-Density Lipoprotein on the Expression of CD36 and Peroxisome Proliferator Activated Receptor Gamma ... Conclusion : It was confirmed that both EPA and ox-LDL increased CD36 expression but not PPAR-?, and also co-treatment with PPAR-? inhibitor decreased CD36 expression
Endemann et al., J Biol Chem 1993 : CD36 may play a role in scavenging LDL modified by oxidation and may mediate effects of OxLDL on monocytes and platelets in atherosclerotic lesions