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AGTR2 — TGFB1
Text-mined interactions from Literome
Yoshiji et al., Hepatology 2001
(Liver Cirrhosis, Experimental) :
Our in vitro study showed that
AT-II increased the
TGF-beta(1) mRNA expression in the activated HSCs, and this effect was totally blocked by CA
Yoshiji et al., J Gastroenterol Hepatol 2007
(Liver Cirrhosis) :
An intrahepatic RAS is expressed in chronically damaged livers, and
angiotensin-II (AT-II) reportedly stimulates contraction and proliferation of the activated hepatic stellate cells ( Ac-HSC ), and
increases the
transforming growth factor-beta ( TGF-beta ) expression through angiotensin type-I receptors (AT1-R)
Li et al., Mol Cell Endocrinol 1998
:
In R3T3 LP, IGF-1 and bFGF, but not
TGFbeta1 , slightly stimulated cell proliferation, but the three factors, specially bFGF,
reduced AT2 expression