Gene interactions and pathways from curated databases and text-mining

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AGTR2 — TGFB1

Text-mined interactions from Literome

Yoshiji et al., Hepatology 2001 (Liver Cirrhosis, Experimental) : Our in vitro study showed that AT-II increased the TGF-beta(1) mRNA expression in the activated HSCs, and this effect was totally blocked by CA
Yoshiji et al., J Gastroenterol Hepatol 2007 (Liver Cirrhosis) : An intrahepatic RAS is expressed in chronically damaged livers, and angiotensin-II (AT-II) reportedly stimulates contraction and proliferation of the activated hepatic stellate cells ( Ac-HSC ), and increases the transforming growth factor-beta ( TGF-beta ) expression through angiotensin type-I receptors (AT1-R)
Li et al., Mol Cell Endocrinol 1998 : In R3T3 LP, IGF-1 and bFGF, but not TGFbeta1 , slightly stimulated cell proliferation, but the three factors, specially bFGF, reduced AT2 expression