Nie et al., International journal of physiology, pathophysiology and pharmacology 2011
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We also found that AGK2 , a selective SIRT2 inhibitor , can exacerbate H2O2 induced decreases in the intracellular ATP level of these cells
Suzuki et al., J Med Chem 2012
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Enzyme assays using recombinant SIRT1 and SIRT2 revealed that 3'-phenethyloxy-2-anilinobenzamide analogues such as 33a and 33i are potent and selective SIRT2 inhibitors, showing more than 3.5-fold greater SIRT2-inhibitory activity and more than 35-fold greater SIRT2-selectivity compared with AGK2 ( 3 ), a previously reported SIRT2-selective inhibitor