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ADCY9 — FGFR3
Text-mined interactions from Literome
Onali et al., Mol Pharmacol 1983
:
Pre-exposure of striatal membranes to guanosine-5'-O- ( 3-thiotriphosphate ) causes a parallel decrease in the basal and
ACh stimulated GTPase activities and in the ACh induced inhibition of
adenylate cyclase
Pappano et al., Am J Physiol 1982
:
Stimulation of
adenylate cyclase by isoproterenol ( ISO ) was
inhibited by
ACh in the absence and presence of cholera toxin
Onali et al., Mol Pharmacol 1983
:
In GH3 pituitary cell homogenates,
acetylcholine (ACh) ( IC50 200 nM )
inhibits adenylate cyclase [ ATP pyrophosphate-lyase ( cyclizing ), EC 4.6.1.1 ] activity in a concentration- and GTP dependent manner ...
ACh reduces the
adenylate cyclase stimulation by vasoactive intestinal peptide (VIP), without changing its EC50
Olianas et al., J Neurochem 1983
:
We investigated the
effect of
acetylcholine (ACh) on the activation of
adenylate cyclase by dopamine ( DA ) in a lysed synaptosomal preparation from rat striatum ...
ACh reduced both basal and the DA-activated
adenylate cyclase with an apparent IC50 of approximately 1 microM ... Inhibition of adenylate cyclase by ACh appeared to be rather specific for activation by DA, as
ACh had no effect on activation of
adenylate cyclase by the adenosine analogue N6- ( L-2-phenylisopropyl ) adenosine
Altenberg et al., Am J Physiol 1994
:
In conclusion, the effect of
ACh is
mediated by inhibition of
adenylate cyclase
Login et al., Brain Res 1996
:
Fractional [ 3H ] ACH efflux from dissociated rat striata tested whether tonic inhibition prevents
stimulation of
acetylcholine (ACH) release by
adenylate cyclase ... Thus, stimulation of
adenylate cyclase within striatal cholinergic interneurons
increases ACH secretion but is tonically inhibited by endogenous striatal transmitters
Login et al., Neuroreport 1997
:
Thus, activation of striatal muscarinic cholinergic autoreceptors potently inhibits basal and
adenylate cyclase stimulated
ACh release
Morita et al., J Biol Chem 1997
:
These and previous findings that
ACh activates
adenylate cyclase by Ca2+ influx in chromaffin cells suggested that ACh induces activation of ADP-ribosyl cyclase through Ca2+ influx and cyclic AMP mediated pathways