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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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ADA — CD4

Text-mined interactions from Literome

Blanco et al., FEBS Lett 2000 : In cells lacking human CXCR4 expression, this gp120 mediated inhibition of ADA binding to human CD26 was completely dependent on the expression of human CD4 ... These data suggest that the interaction of gp120 with CD4 or CXCR4 is required for efficient inhibition of ADA binding to CD26, although in the presence of CXCR4 the interaction of gp120 with CD4 may be dispensable
Benveniste et al., Proc Natl Acad Sci U S A 1995 : We demonstrate that ADA deficiency causes depletion of CD8low transitional and CD4+CD8+ double positive thymocytes by an apoptotic mechanism