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NOS3 — PLCG1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Ahmad et al., Circ Res 2006
:
Activation of eNOS by VEGFR-1 was dependent on Tyr794 and was mediated via phosphatidylinositol 3-kinase, whereas VEGFR-2 Tyr951 was involved in
eNOS activation via
phospholipase Cgamma1
Bates et al., Cardiovasc Res 2010
:
Detailed analysis of the published literature has shown that in vivo and in vitro VEGF mediated permeability differs in its time course, but has common involvement of many specific signalling pathways, in particular VEGF receptor-2 activation, calcium influx through transient receptor potential channels,
activation of
phospholipase C gamma and downstream activation of
nitric oxide synthase