Kato et al., Biochem J 2006
:
When triggered by laminins, NEU3 clearly stimulated phosphorylation of FAK ( focal adhesion kinase ) and ERK ( extracellular-signal regulated kinase ), whereas there was no activation on fibronectin
Cronan et al., Oncogene 2012
(Breast Neoplasms...) :
MEKK2 was required for epidermal growth factor receptor and Her2/Neu activation of ERK5 , with ERK5 being required for metastasis