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IFNG — IGF2
Text-mined interactions from Literome
Shalita-Chesner et al., Mol Cell Endocrinol 2001
:
This effect was associated with significant reductions in the levels of IGF-l-R mRNA and protein, and with inhibition of IGF-l-R promoter activity, suggesting that TNF-alpha and
IFN-gamma affect
IGF-l-R gene expression at the transcriptional level
Anwar et al., Circulation 2002
(Arteriosclerosis) :
IL-1beta, IL-6, and
IFN-gamma did not
regulate IGF-1, IGF-1 receptor (R), or
IGF binding proteins ( IGFBPs )
Shalita-Chesner et al., J Pediatr Endocrinol 2004
(Bone Neoplasms...) :
The potential involvement of STAT proteins in transcriptional
regulation of the
IGF-IR gene by
IFN-gamma was addressed by transient coexpression of vectors encoding STAT1 and STAT5b, together with an IGF-IR promoter luciferase reporter, in the osteosarcoma derived cell line Saos-2
Jia et al., Am J Physiol Heart Circ Physiol 2007
(Carotid Artery Diseases...) :
Here we assessed the expression of IGF-I receptor (IGF-IR) in atherosclerotic plaques and in plaque VSMCs of asymptomatic and symptomatic patients with carotid stenosis and examined the
effect of IGF-I, IL-12, and
IFN-gamma on the expression of
IGF-IR and IGF binding protein (IGFBP)-3 in plaque VSMCs
Hu et al., Mol Hum Reprod 2008
:
IFN-gamma relatively
increased IGF-1 and -2 secretion
Ilvesmäki et al., Mol Cell Endocrinol 1993
:
Tumor necrosis factor-alpha and
interferon-gamma inhibit
insulin-like growth factor II gene expression in human fetal adrenal cell cultures
Martin et al., J Neurosci Res 1993
(Brain Neoplasms...) :
Interferon-gamma inhibits DNA synthesis and
insulin-like growth factor-II expression in human neuroblastoma cells ... In this study, we determined the
effects of
IFN-gamma on cellular growth and expression of
insulin-like growth factor II (IGF-II) and IGF receptors in the human neuroblastoma cell line SH-SY5Y