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EGF — GTPBP3
Text-mined interactions from Literome
Hart et al., J Biol Chem 1990
:
The identification and characterization of an
epidermal growth factor stimulated phosphorylation of a specific low molecular weight
GTP binding protein in a reconstituted phospholipid vesicle system ... The
EGF stimulated phosphorylation of this
GTP binding protein is also markedly attenuated by guanine nucleotides, i.e. GTP, GTP gamma S, or GDP, suggesting that maximal phosphorylation occurs when the GTP binding protein is in a guanine nucleotide depleted state ... When highly purified preparations of the human platelet Gp ( G25K ) protein are reconstituted with the purified EGF receptor into phospholipid vesicles, an
EGF stimulated phosphorylation of the platelet
GTP binding protein occurs with a stoichiometry approaching 2 mol of 32Pi incorporated/mol of [ 35S ] GTP gamma S-binding sites ... As is the case for the brain 22-kDa protein, the
EGF stimulated phosphorylation of the platelet
GTP binding protein is attenuated by guanine nucleotides
Simpson et al., Nat Cell Biol 2012
:
Network analyses revealed a so far unappreciated link between early secretory pathway function, small
GTP binding protein regulation , actin cytoskeleton organization and
EGF-receptor mediated signalling
Kuryshev et al., Cell Signal 1993
:
Evidence for
involvement of a
GTP binding protein in activation of Ca2+ influx by
epidermal growth factor in A431 cells : effects of fluoride and bacterial toxins