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BCAR1 — EGF

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: Complex of BCAR1-PTK2-TNS3 → EGF (decreases, BCAR1/PTK2/TNS3 Activity) Cui et al., Mol Cancer Res 2004*
  Evidence: Furthermore, tensin3 forms a complex with focal adhesion kinase and p130Cas in MDA-MB-468 cells. Addition of EGF to the cells induces dephosphorylation of these two molecules, leads to disassociation of the tensin3-focal adhesion kinase-p130Cas complex, and enhances the interaction between tensin3 and EGF receptor.
• OpenBEL Selventa BEL large corpus: BCAR1 → EGF (decreases) Cui et al., Mol Cancer Res 2004*
  Evidence: Addition of EGF to the cells induces dephosphorylation of these two molecules, leads to disassociation of the tensin3-focal adhesion kinase-p130Cas complex, and enhances the interaction between tensin3 and EGF receptor.

Text-mined interactions from Literome

Take et al., Biochem Biophys Res Commun 2000 : Our results suggest that CIN85 may play a specific role in the EGF receptor mediated signaling cascade via its interaction with c-Cbl
Kowanetz et al., J Biol Chem 2003 : Identification of a novel proline-arginine motif involved in CIN85 dependent clustering of Cbl and down-regulation of epidermal growth factor receptors