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ICAM1 — PARP12
Text-mined interactions from Literome
Sharp et al., Inflammation 2001
(Inflammation) :
Enzyme linked immunosorbent analysis ( ELISA ) was used to assess if
ICAM-1 , VCAM-1, and E-selectin were expressed at the cell surface, and if
PARP inhibition ( using the selective PARP inhibitor GPI 6150 )
blocked the induced expression ...
PARP inhibition with GPI 6150 blocked the IL-1beta mediated stimulation of both ICAM-1 and E-selectin expression, and
blocked TNF-alpha stimulation of
ICAM-1 expression at 24 h
Cuzzocrea et al., Biochem Pharmacol 2002
(Disease Models, Animal...) :
The potent
PARP inhibitor 5-aminoisoquinolinone ( 5-AIQ ) reduced the degree of lung injury and
attenuated the expression of P-selectin and
ICAM-1 as well as the recruitment of neutrophils into the injured lung
Cuzzocrea et al., Shock 2004
(Reperfusion Injury...) :
Administration of WY 14643 also markedly reduced the nitrotyrosine formation, poly ( adenosine diphosphate [ ADP ] -ribose ) polymerase (
PARP )
activation , up-regulation of
ICAM-1 , and expression of P-selectin during reperfusion
Qin et al., Biochim Biophys Acta 2013
(Inflammation) :
Moreover,
PARP-1 inhibition
attenuated LSS induced iNOS and
ICAM-1 upregulation by inhibiting nuclear factor kappa B ( NF-?B ) nuclear translocation and activity, with a reduced NF-?B phosphorylation