Birch et al., Eur J Biochem 1991
:
Ca2+ stimulated the first cleavage of pro-opiomelanocortin by pro-opiomelanocortin converting enzyme to yield 21-23 kDa adrenocorticotropin and beta-lipotropin, but its effect was minimal
Lorsignol et al., J Neuroendocrinol 1998
:
Of the cells showing Ca2+ response to POMC1-76 , approximately one-third contained GH and another third prolactin ... The present data show that, in immature pituitary cells, POMC1-76 induces an increase in [ Ca2+ ] i through extracellular Ca2+ influx, possibly mediated in part by protein kinase A activation