Iljin et al., Cancer Res 2006
(Prostatic Neoplasms) :
Activation of ERG by fusion with TMPRSS2 may lead to epigenetic reprogramming, WNT signaling, and down-regulation of cell death pathways, implicating ERG in several hallmarks of cancer with potential therapeutic importance
Li et al., Cancer prevention research (Philadelphia, Pa.) 2011
(Neoplasm Invasiveness...) :
Moreover, we found that ERG overexpression and nuclear translocation activated the activity of Wnt signaling