Vogel et al., J Clin Endocrinol Metab 2005
(Adrenal Gland Neoplasms...) :
Studies in other VHL associated tumors suggest that VHL gene deficiency causes coexpression of erythropoietin (Epo) and its receptor ( Epo-R ), which facilitates tumor growth
Vogel et al., J Neurosurg 2005
(Ear Neoplasms...) :
Data from previous studies of VHL disease associated hemangioblastomas ( HBs ) and renal cell carcinomas ( RCCs ) have indicated that VHL gene deficiency causes coexpression of erythropoietin (Epo) and its receptor ( Epo-R ), which facilitates tumor growth
Krieg et al., Blood 1998
(Brain Neoplasms...) :
These results suggest that in the nonhypoxic microenvironment of hemangioblastoma, Epo , similar to VEGF, might be negatively regulated by the VHL gene product