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ABCB1 — SETD2
Text-mined interactions from Literome
Comerford et al., Cancer Res 2002
(Cell Transformation, Neoplastic) :
Examination of the MDR1 gene identified a binding site for hypoxia inducible factor-1 (HIF-1), and inhibition of
HIF-1 expression by antisense oligonucleotides
resulted in significant inhibition of hypoxia-inducible
MDR1 expression and a nearly complete loss of basal MDR1 expression
Zhang et al., Dis Esophagus 2011
(Esophageal Neoplasms) :
Silencing of
HIF1a decreased MDR1 expression and
blocked changes in
MDR1 and HIF1a expression induced by fractioned irradiation
Chou et al., Neuro Oncol 2012
(Anoxia...) :
Cycling hypoxia plays a vital role in tumor microenvironment mediated chemoresistance through the
HIF-1 dependent induction of
ABCB1