Gene interactions and pathways from curated databases and text-mining

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GPER1 — NOS3

Text-mined interactions from Literome

Haynes et al., Circ Res 2000 : Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells
Wang et al., Sheng Li Xue Bao 2003 : [Membrane estrogen receptor mediates the rapid nongenomic activation of endothelial nitric oxide synthase by estrogen ]
Li et al., PloS one 2012 (Body Weight...) : These findings provide preliminary evidence that GPR30 activation leads to eNOS activation, as well as vasodilation, to a certain degree and has beneficial effects on vascular function in diabetic OVX rats