Gene interactions and pathways from curated databases and text-mining

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NOS1 — SOD3

Text-mined interactions from Literome

Didier et al., FASEB J 1999 : Cells were also treated either with L-thiocitrulline ( L-Thio ), an irreversible inhibitor of NOS , or with exogenous superoxide dismutase ( SOD ) and catalase
González et al., Braz J Med Biol Res 2000 (Diabetes Mellitus, Experimental) : Moreover, inhibition of NOS activity produces an increase in SOD activity and a decrease in lipoperoxidation in diabetic pancreatic tissues
Hu et al., Acta Pharmacol Sin 2001 (Disease Models, Animal...) : In the rat peritonitis induced by carrageenan, rh-bFGF 4 kU/kg decreased the MDA and NO levels, inhibited the NOS activity, augmented the SOD activity, and lowered the production of PGE ( 2 ) in exudate
Kawahara et al., Free radical research 2002 (Glioma...) : This increased resistance to NO toxicity in differentiated cells was almost completely cancelled out by inhibiting the activity of superoxide dismutase ( SOD ) , but not by inhibiting the activity of NOS
Hu et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 2007 (Brain Ischemia...) : After being treated with the combination of both TA, the average neurological score, cerebral infracted volume, cerebral water content, activity of NOS and content of MDA in the model rats significantly decreased, and the activity of SOD was significantly increased ( all P < 0.05 )
Baldelli et al., Int J Biochem Cell Biol 2008 : nNOS increase also mediates a down-regulation of copper, zinc superoxide dismutase ( SOD1 ) in terms of mRNA production, protein and activity levels
Lee et al., Exp Mol Med 2009 : Differential regulation of inducible nitric oxide synthase and cyclooxygenase-2 expression by superoxide dismutase in lipopolysaccharide stimulated RAW 264.7 cells
Liu et al., Brain Res 2012 (Disease Models, Animal...) : The results showed that after PFC administration, the latency to first electrical discharge in EEG was significantly shortened ; MDA, H ( 2 ) O ( 2 ), NO levels and NOS activity increased ; and SOD , GPx and CAT activities decreased
Berman et al., Br J Pharmacol 1993 : 3. The increase in albumin transfer induced by hypoxanthine and xanthine oxidase was abolished by catalase ( 3 u ml-1 ), reduced by allopurinol ( 4 mM ), but unaffected by superoxide dismutase ( 6000 u ml-1 ), the hydroxyl radical scavengers, mannitol ( 15 mM ), dimethylthiourea ( 10 mM ) and N- ( 2-mercaptopropionyl ) -glycine ( 1 mM ), the iron chelator, deferoxamine ( 0.5 mM ), ferric chloride ( 50 microM ), an inhibitor of nitric oxide synthase , NG-nitro-L-arginine ( 30 microM ), or the antioxidant, dithiothreitol ( 3 mM )
Allen et al., J Infect Dis 1997 : The possibility that peroxynitrite contributes to this maximum luminol dependent activity was tested, but neither superoxide dismutase , a competitive inhibitor of peroxynitrite production, nor N-methyl-L-arginine, an inhibitor of nitric oxide synthase , exerted a significant inhibitory effect
Nelson et al., Hum Reprod 1998 : In both P and NP arteries the cholinergic relaxation was increased in the presence of superoxide dismutase and greatly reduced in the presence of the nitric oxide synthase inhibitors, NG-mono-methyl L-arginine ( L-NMMA ) and L-nitro-arginine-methylester ( L-NAME )