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IRF6 — STAT5A

Text-mined interactions from Literome

Stoiber et al., J Immunol 1999 : Further consistent with inhibitory activity of SOCS3, LPS also inhibited the JAK2 dependent activation of Stat5 by GM-CSF
Kimura et al., Proc Natl Acad Sci U S A 2005 : We found that LPS directly activated Jak2 and Stat5 , whereas SOCS-1 inhibited LPS induced Jak2 and Stat5 activation
Huang et al., J Clin Invest 2007 (Inflammation...) : Enforced expression of STAT1, IRF-1 , or GATA-1 enhanced phosphorylation of STAT1, STAT3, and STAT5 in cultured Gata1-deficient murine megakaryocytes, with concomitant megakaryocyte maturation
Nam et al., J Pept Sci 2012 : Western blotting revealed that LPS induced activation of STAT1 and STAT5 in macrophages was significantly inhibited by CopA3
Yamaoka et al., J Immunol 1998 : Consequently, LPS induced activation of STAT5 in human monocytes, and this STAT5 activation occurred in an indirect way via granulocyte-macrophage CSF (GM-CSF) secreted by LPS stimulated monocytes ... Taken together, these results suggest that in addition to other transcription factors, STAT5 plays an important role in activation of monocytes by LPS , and that STAT5 is another target for IL-10 and Dex to inhibit COX-2 expression in activated monocytes