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IRF6 — PTEN

Text-mined interactions from Literome

He et al., PloS one 2012 : In addition, siRNA mediated knockdown of TLR4 inhibited the LPS induced up-regulation of TLR4, down-regulation of PTEN , and activation of the PI3K-Akt pathway ( overexpression of phospho-Akt ) at 72 hours, as detected by real-time PCR and Western blot analysis ... Neither the baseline expression nor LPS induced down-regulation of PTEN in lung fibroblasts was influenced by PI3K activation state
Ke et al., Hepatology 2013 (Disease Models, Animal...) : In contrast, knockdown of ß-catenin increased PTEN/TLR4 ( Toll-like receptor 4 ), interferon regulatory factor-3 (IRF3), nuclear factor kappa B ( NF-?B ) activity, and proinflammatory cytokine programs in response to LPS stimulation