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IRF6 — MDM1

Text-mined interactions from Literome

Xiong et al., J Neurovirol 1999 (AIDS Dementia Complex...) : Synaptic strength was enhanced in virus infected ( 135.7+/-28.9 %, n=8 ) and LPS activated MDM ( 123.3+/-5.1 %, n=7 ) but at lower levels than controls
Zheng et al., Neurotox Res 2001 : Rat cortical and hippocampal neurons were exposed to secretory products from HIV-1 infected and lipopolysaccharide (LPS) activated human monocyte derived macrophage ( MDM )
Varney et al., J Interferon Cytokine Res 2005 (Melanoma...) : Further activation of monocytes and monocyte derived macrophages ( MDM ) by lipopolysaccharide (LPS) caused an increase in VEGF-A expression
Benoit et al., Eur J Immunol 2008 (Q Fever) : Functional analyses showed that C. burnetii stimulated MDM produced high levels of TGF-beta1 and CCL18, and expressed the mannose receptor and arginase-1, the latter being associated with the prevention of nitric oxide production by MDM. Finally, C. burnetii induced the release of IL-6 and CXCL8 at a lower level than LPS stimulated MDM. Our results suggest that C. burnetii stimulated an atypical M2 activation program that may account for the persistence of C. burnetii in macrophages
Peng et al., Glia 2008 (HIV Infections) : Conditioned media from lipopolysaccharide (LPS) activated MDM ( LPS-MCM ) or HIV infected MCM ( HIV-MCM ) induced a profound increase in NPC proliferation
Ferrara et al., Scand J Immunol 2008 (Tuberculosis, Pulmonary) : Stimulation of MDM with LPS or MTB led to a significant increase in CCL18 protein ( control 2.67 +/- 0.46 ng/ml, LPS 4.05 +/- 0.56 ng/ml, with MTB 6.70 +/- 1.59 ng/ml, n = 5, P < 0.05 ) and specific mRNA levels ( control 0.09 +/- 0.01, LPS 0.24 +/- 0.11, with MTB 0.34 +/- 0.08 CCL18/Glyceraldehyde 3-phosphate dehydrogenase ( GAPDH ), n = 3, P < 0.05 )
Hu et al., Glia 2009 : To understand how activated macrophages induce neuronal dysfunction and injury, we studied the effects of lipopolysaccharide (LPS) stimulated human monocytes derived macrophage ( MDM ) on neuronal outward delayed rectifier K ( + ) current ( I ( K ) ) and resultant change on neuronal viability in primary rat hippocampal neuronal culture
Burian et al., Peptides 2010 (Inflammation...) : A similar receptor expression pattern was also observed in lipopolysaccharide (LPS) activated monocyte derived macrophages ( MDM ) from healthy volunteers and COPD patients
Hu et al., Eur J Neurosci 2010 : To test our hypothesis that activated macrophages induce neuronal injury by enhancing neuronal outward K ( + ) current, we studied the effects of lipopolysaccharide (LPS) stimulated human monocyte derived macrophage ( MDM ) on neuronal transient A-type K ( + ) current ( I ( A ) ) and resultant neuronal injury in primary rat hippocampal neuronal cultures
Sipka et al., Vet Immunol Immunopathol 2010 (Inflammation) : Stimulation of monocytes and MdM with lipopolysaccharide (LPS) for 3h did not alter the expression level of NK-1R
Zhou et al., Biochem Biophys Res Commun 2013 (HIV Infections) : We show that LPS activated MDM both inhibited HIV-1 entry into the cells and were refractory to post-entry productive viral replication ... LPS activation of MDM markedly enhanced the expression of heme oxygenase-1 (HO-1), a potent inducible cytoprotective enzyme ... Increased HO-1 expression was accompanied by elevated production of macrophage inflammatory chemokines ( MIP1a and MIP1ß ) by LPS activated MDM , significantly decreased surface chemokine receptor-5 (CCR-5) expression, and substantially reduced virus replication