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ABCA1 — IRF6
Text-mined interactions from Literome
Baranova et al., Infect Immun 2002
:
In addition, we compared the potencies of various modified LPS preparations and demonstrated that the phosphorylated lipid A portion of LPS, which is highly conserved among gram negative microorganisms, including Chlamydia, is primarily responsible for the
effects of
LPS on SR-B1 and
ABCA1 expression ... Inhibitors of NF-kappaB activation were observed to efficiently block the suppressive
effect of
LPS on SR-B1 and
ABCA1 , suggesting a mechanism involving NF-kappaB
Kaplan et al., J Lipid Res 2002
:
Together, these studies show that
LPS regulates
ABCA1 expression through an LXR independent mechanism ... Therefore, this suggests that both transport of LPS from the plasma membrane to an intracellular site and activation of p38 MAP kinase are involved in the
LPS mediated induction of
ABCA1
Andersson et al., J Cyst Fibros 2008
(Cystic Fibrosis...) :
This was associated with low basal PPARgamma expression and attenuated
LPS induced induction of PPARdelta, LXRalpha and
ABCA1
Lee et al., Dig Dis Sci 2008
(Inflammation) :
WY-14643, troglitazone, and
LPS also
induced an increase in the expression of
ABCA1 protein and mRNA in cultured GBEC