Gene interactions and pathways from curated databases and text-mining

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IRF1 — TRIM22

Text-mined interactions from Literome

Gao et al., J Immunol 2010 : Moreover, overexpression of IRF-1 significantly induced TRIM22 expression, whereas silencing of IRF-1 with specific short interference RNA abolished IFN-gamma induced TRIM22 expression in HepG2 cells, indicating an IRF-1 dependent expression of TRIM22
Gao et al., Eur J Immunol 2013 : We further show that p300 contributed to both IFN-?- and IRF-1 mediated TRIM22 transcription independent of its histone acetyltransferase activity, however, it was required for the recruitment of RNA polymerase II to TRIM22 promoter region