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IL8 — PLAU
Text-mined interactions from Literome
Michi et al., Oral Oncol 2000
(Carcinoma, Squamous Cell...) :
In contrast, neither
anti-interleukin-8 (IL-8) antibody nor anti-hepatocyte growth factor ( HGF beta ) antibody
affected uPA activity in the endothelial cells
Han et al., J Surg Res 2002
:
In this report, we show that
interleukin-8 (IL-8) , but not other cytokines tested, is a potent
inducer of the 38-kDa
uPA in organ cultured human skin ... In addition, the
uPA inhibitor, PAI-1, was not
affected by
IL-8 ... The mRNA expression of
uPA in the keratinocytes was found to be constitutively elevated and was not
affected by
IL-8
So et al., Gynecol Oncol 2004
(Neoplasm Invasiveness...) :
IL-8 did not
affect cellular migration, MMP2 activation, or
uPA expression
Dulak et al., Endothelium : journal of endothelial cell research 2005
:
Importantly, atorvastatin at the micromolar concentrations diminished the production of
interleukin (IL)-8 , a proinflammatory and proangiogenic chemokine, and
inhibited the synthesis of
urokinase plasminogen activator (uPA) , a potent proinflammatory mediator