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IL8 — PGP

Text-mined interactions from Literome

Sugawara et al., Infect Immun 2001 : PGP induced a high level of interleukin-8 production at doses of 100 ng/ml and higher in OCT treated THP-1 cells compared with Salmonella LPS, and the production was significantly inhibited by anti-CD14 and anti-TLR2 but not anti-TLR4 antibodies
Bonhomme-Faivre et al., Anticancer Drugs 2002 : Based on the premise that Taxol pharmacokinetic parameters could be modified as a result of diminished P-gp expression induced by recombinant interleukin ( rIL ) -2 and that this might elicit an interaction between the two drugs, we evaluated the pharmacokinetics of a novel strategy combining i.p. immunotherapy with rIL-2 and a cytotoxic agent, Taxol