◀ Back to CA2
CA2 — MTX1
Text-mined interactions from Literome
Nakahata et al., Toxicon 1999
:
Thus,
MTX is similar to U46619 in functions of Ca2+ mobilization, phosphoinositide hydrolysis and tyrosine phosphorylation, but MTX induced actions are strictly
dependent on the presence of external
Ca2+
Alfonso et al., Biochem Pharmacol 2005
(Calcium Signaling) :
AZ-4 also inhibited
maitotoxin (MTX) stimulated
Ca2+-influx by 5-10 %
Treviño et al., J Cell Physiol 2006
:
In addition,
MTX significantly
increased [
Ca2+ ] i in single mature sperm and effectively induced the AR with a half-maximal concentration ( ED50 ) of approximately 1.1 nM
Pin et al., J Neurochem 1988
:
MTX also
induced a massive accumulation of
45Ca2+ in the neurons which, in contrast to the MTX evoked GABA release, was totally blocked in the presence of 1 mM Co2+ ... It is concluded that, on striatal neurons,
MTX induced Na+ influx only in the
presence of external
Ca2+
Watanabe et al., Br J Pharmacol 1993
(Ion Channel Gating) :
The cytosolic
Ca2+ concentration ([Ca2+]i) , measured by fura-2 fluorescence technique, was also
increased by the presence of
MTX