Gene interactions and pathways from curated databases and text-mining

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CA2 — GRP

Text-mined interactions from Literome

Slice et al., Receptors Channels 1998 : In comparison with epithelial cells expressing wild-type GRPR, the GRPR-GFP expressing cells showed similar ligand binding affinity, GRP stimulated Ca2+ signaling, and GRP initiated internalization
Karlsson et al., Biochem Biophys Res Commun 2001 (Calcium Signaling) : Direct cytoplasmic CA(2+) responses to gastrin releasing peptide in single beta cells
Woll et al., Cancer Res 1990 (Carcinoma, Small Cell...) : It also blocked receptor mediated Ca2+ mobilization induced by vasopressin, bradykinin, cholecystokinin, galanin, gastrin releasing peptide , and neurotensin
Karlsson et al., Peptides 1996 : Furthermore, the GRP induced increase in [ Ca2+ ] ic was potentiated by forskolin and impaired by activation of protein kinase C ( PKC ) by 12-O-tetradecanoyl-phorbol-13-acetate ( TPA )
Gregersen et al., Pancreas 1996 : Similarly, GRP increased 86Rb+ efflux from 86Rb ( + ) -prelabeled islets both in the presence and in the absence of extracellular Ca2+ ( p < 0.001 )
Sharif et al., Mol Cell Endocrinol 1997 (Glioblastoma) : Bombesin and GRP induced the release of cytosolic Ca2+ in a concentration dependent manner