◀ Back to BCL6

BCL6 — CNTN2

Text-mined interactions from Literome

Mori et al., Virus Genes 2001 (Leukemia, T-Cell) : We have recently demonstrated that Tax induces the constitutive expression of the anti-apoptotic protein, Bcl-xL , in a mouse T-cell line ... We thus examined whether Tax also activates the expression of Bcl-xL in human T-cells ... Expression of Tax in a human T-cell line, Jurkat, induced the expression of the Bcl-xL gene, but did not significantly affect the expression of the other apoptosis related genes, Bcl-2 and Bax ... Transient transfection assays showed that Tax stimulated human Bcl-xL promoter activity in Jurkat cells
Dean et al., Oncogene 2009 (HTLV-I Infections) : Using functional assays, we demonstrate that Tax 1 enhanced the repressive activity of BCL6 and increased the levels of apoptosis induced by BCL6 in osteosarcoma cells indicating that both proteins cooperate in vivo to cause a physiological affect