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WNT11 — WNT2
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Le Floch et al., FASEB J 2005
(Colonic Neoplasms...) :
Upstream
activation of
Wnt signaling by the Wnt-2 and Wnt-3a ligands, stable overexpression of
Wnt-2 , as well as GSK-3beta inhibition by lithium, SB216763, and GSK-3beta dominant negative forms ( K85R and R96E ) conferred the invasive phenotype through several proinvasive pathways
Shi et al., Int J Cancer 2007
(Colorectal Neoplasms) :
In this study, we investigated
roles of
Wnt-2 and Gal-3 in the regulation of canonical
Wnt/beta-catenin signaling
Bayle et al., J Invest Dermatol 2008
(Scleroderma, Systemic) :
Increased expression of
Wnt2 and SFRP4 in Tsk mouse skin :
role of
Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis
Hardy et al., Dev Biol 2008
:
We conclude that non-canonical
Wnt signaling,
mediated in part by
Wnt11b , is important for regulation of gastrulation cell movements in the avian embryo
Katoh et al., Int J Mol Med 2009
:
Canonical
WNT signals and GATA family members are
involved in
WNT11 transcription during embryogenesis of model animals ; however, precise mechanisms of WNT11 expression remain unclear
Uysal-Onganer et al., Acta Physiol (Oxf) 2012
(Neoplasms...) :
We highlight an emerging theme in which canonical
Wnt signals
regulate Wnt11 expression through transcription factors in addition to, or other than, Tcf/LEF family members