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ATP5O — WNT16
Text-mined interactions from Literome
Cruciat et al., Science 2010
:
Moreover, PRR and
V-ATPase were
required to mediate
Wnt signaling during antero-posterior patterning of Xenopus early central nervous system development
Sihn et al., Kidney Int 2010
(Cardiovascular Diseases...) :
Notably, lack of the protein in vertebrates leads to developmental alterations and early embryonic lethality probably as a
result of the recently discovered role of the ( pro ) renin receptor and the vacuolar H ( + )
-ATPase in
Wnt signaling
Coombs et al., J Cell Sci 2010
:
Inhibition of the
V-ATPase or disruption of vacuolar pH gradients by diverse drugs potently
inhibited Wnt/ß-catenin signaling both in cultured human cells and in vivo, and impaired Wnt regulated convergent extension movements in Xenopus embryos