Kim et al., Mol Cancer Res 2005
(Colorectal Neoplasms) :
Finally, treatment of HCT-116-15-LOX-1 cells with different kinase inhibitors suggested that the effects of 15-LOX-1 on p53 phosphorylation and activation were due to effects on DNA dependent protein kinase
Zhu et al., Int J Cancer 2008
(Colorectal Neoplasms...) :
Thus, 15-LOX-1 induces p53 phosphorylation independent of enzymatic activity