Chang et al., Mol Pharmacol 2004
:
One is the JAK1/2 dependent PLC-gamma pathway inducing the activations of PKCalpha , c-Src, and STAT1, and the other is the direct activation of STAT1 by JAK1/2
Hardy et al., Immunology 2009
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Finally, PKC-alpha associated with signal transducer and activator of transcription 1 ( STAT1 ) and was required for the phosphorylation of STAT1 on serine 727 in IFN-gamma stimulated macrophages