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Blanco-Colio et al., Atherosclerosis 2002
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In addition, overexpression of constitutively active Q63L Rho A prevented , at least in part, apoptosis induced by statins and downregulation of Bcl-2 Gómez et al., Eur J Immunol 1997
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IL-2, but not IL-4, induces Bcl-2 expression through RhoA activation which is inhibited by the specific Rho family inhibitor, Clostridium difficile Toxin B, as well as by a dominant negative RhoA mutant